Rx
Generic BenzaClin®

Clindamycin 1% and benzoyl peroxide 5% gel

Clindamycin and benzoyl peroxide is a combination topical antibiotic gel that may be prescribed to treat acne-causing bacteria.

Acne Icon Acne
Topical gel Icon Topical gel

$35/month

As low as $0/mo with insurance

Medication costs vary based on prescribed treatment and applicable insurance coverage. Not all insurance plans are accepted. Additional costs apply, including a consultation and support fee. Medication shipped and billed every 2 months. One tube of medication contains a 2-month supply.
This treatment requires an online consultation with a Nurx medical provider. If prescribed, they'll check in to ensure your treatment is working.*

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How clindamycin and benzoyl peroxide treats acne*

  • Stops the growth of bacteria that can accumulate in clogged pores
  • Provides anti-inflammatory benefits that helps skin look more radiant and fresh
Find my treatment
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DID YOU KNOW?

Dynamic duo

Studies show that clindamycin and benzoyl peroxide are more effective at treating acne when combined.

Real patient stories

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REAL RESULTS

Shannon, Nurx patient

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REAL RESULTS

Nathalia, Nurx patient

The science behind it

FACT 01

Antibiotic treatment

Antibiotics are a type of drug used to treat or prevent bacterial infections.

FACT 02

Stops bacteria growth

This medication works by stopping the growth of bacteria that can accumulate in clogged pores.

FACT 03

Anti-inflammatory benefits

This medication also may help reduce swelling and redness for active acne breakouts.

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How to use clindamycin and benzoyl peroxide

Consistency is key to maximizing the effectiveness of your acne treatment. This medication should be used twice per day (ideally in the morning and at night).

Drug facts

Step 1

Wash the affected area with a mild cleanser and allow to dry for at least 15 minutes.

Step 2

Apply a pea-sized amount in a thin layer to the affected area of the skin.

Step 3

Wash hands after use. Wait at least one hour after applying to use non-medicated makeup.

How Nurx works

1

Request treatment

Complete our online medical consultation, which asks questions about your health history and skin concerns.

2

Connect with a provider

After evaluating your consultation, a provider licensed in your state will prescribe treatment (if clinically appropriate).

3

Get it delivered

We’ll send a 3-month supply to your doorstep and check in with you to see how it’s working. Pause or cancel anytime.

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Nurx patients served

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Why Nurx?

Affordable

Quality treatment at an attainable price

Convenient

Easy refills & shipping to your door

Personalized

Providers help you find the right treatment

Supportive

Unlimited messaging for any questions, anytime

Common questions

  • How is clindamycin and benzoyl peroxide gel used?

    Clindamycin and benzoyl peroxide gel is used twice a day, ideally in the morning and again at night. First, wash the affected area with a non-medicated cleanser, then rinse well with warm water. Thoroughly dry the area or wait 15 minutes before applying your medication. Dispense a pea-sized amount of gel to clean fingers and spread a thin layer to the area being treated, the entire face, or as directed by your provider.

    Avoid contact with the mouth, eyes, nose, or anywhere skin may be broken. Rinse thoroughly with cool water if the gel contacts mucous membranes. Wash your hands thoroughly after each use. This product may contain a bleaching risk, so it's best to avoid contact with hair or clothing when applying your medication.

    Be sure to protect your medication from light, moisture, or fluctuations in temperature, especially high temperatures. For these reasons, it's best not to store clindamycin and benzoyl peroxide gel in the bathroom. Keep the container tightly closed and stored at room temperature. Your medication has a limited time that it remains effective. Dispose of any unused medication after three months.

    Since clindamycin and benzoyl peroxide gel is most effective when applied twice at the same time each day, set up a routine for applying your medication after you wake up and before going to bed, so you don't miss a treatment. Please note, your provider may recommend once daily treatment if you are using other acne treatments or have sensitive skin.

  • What precautions should I take before using clindamycin and benzoyl peroxide gel?

    Although clindamycin and benzoyl peroxide gel is safe and effective for most people, those with pre-existing conditions may experience a worsening of their symptoms. This is true for those who have intestinal disorders such as colitis, ulcerative colitis, or regional enteritis. Tell your provider if you have been diagnosed with these conditions to determine if clindamycin and benzoyl peroxide gel is right for you.

    Skin sensitivity may be increased with the use of clindamycin and benzoyl peroxide gel. Avoid sun exposure, tanning booths, and sunlamps while using your medication to decrease the risk of skin discoloration, and use sunscreen to protect the area when you're outside. If you experience a sunburn, let our team know so we can make assessments and get you back on track with your treatment.

    Never increase the dose of your medication or use more than twice a day without speaking to our medical team, as this may increase the risk of side effects and will not improve your acne faster.

    Serious allergic reactions are rare and more likely to occur in those with a history of reactions to benzoyl peroxide, clindamycin, or lincomycin. Tell your medical provider about known allergic reactions. Symptoms of an allergic reaction may include rash, itching, swelling of the face, tongue or throat, dizziness, or trouble breathing. Get medical attention right away if you experience symptoms of an allergic reaction.

  • Are there any known side effects?

    Most clindamycin and benzoyl peroxide gel users do not have serious side effects, and the most common one is dry skin. Erythema, a patchy redness, sometimes occurs, and skin moisturizing creams may help reduce irritation and side effects.

    Itching, burning, and peeling are less common and were reported by less than 6% of users. The most serious side effects are rare and have presented as rash, bloody diarrhea, skin inflammation, eye pain, or skin discoloration.

    If you notice these or other side effects, or if side effects fail to improve or worsen, stop your medication and speak with your Nurx medical provider to determine the best course of action.

  • Can I use clindamycin and benzoyl peroxide gel with other medications?

    Clindamycin and benzoyl peroxide gel is best used alone and not combined with other acne medications unless your provider has approved their use. Since this is a medication, it can interfere with other prescription, over-the-counter, or herbal medications or remedies.

    Tell your Nurx provider what medications or supplements you may be taking to ensure clindamycin and benzoyl peroxide gel is the right treatment for you. To reduce the risk of side effects or interactions, always follow your prescription and don't increase your dose or frequency of use without a provider's approval.

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DR. PETER YOUNG, MEDICAL DIRECTOR

Meet your medical team

Peter Young, MD is the Medical Director for Nurx’s Dermatology specialty. Dr. Young is a board-certified dermatologist who advises the Nurx medical team on how to provide the highest quality of care for dermatology conditions through telehealth.

†Clindamycin 1% and benzoyl peroxide 5% gel, Rx only, treats acne. This drug may cause side effects, including dry skin and application site reaction. If you would like to learn more, see full prescribing information here. You are encouraged to report negative side effects to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
*Individual results may vary.
‡The information provided here is not a substitute for professional medical advice, diagnosis, or treatment. You should not rely upon the content provided here for specific medical advice. If you have any questions or concerns, please talk to your provider.
◊Services not offered in every state. Medications prescribed only if clinically appropriate, based on completion of the required consultation.

Talk to our experts

Not sure if this medication is right for you?

Connect with a Nurx provider for a personalized treatment recommendation.

Exceptional care at every step

At Nurx, we make it easy to get the expert healthcare you deserve. From schedules to health history, everybody is different—so we provide treatment and care that’s personalized to you. Through life’s cycles, changes, and transitions, we’re here to help you make informed choices about your health.

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