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A prescription bottle labeled
Rx
4.8 26,564 Nurx Reviews
Based on all Nurx reviews, not any one product
Rx
Generic Zoloft®

Sertraline HCl

4.8
26,564 Nurx Reviews
Based on all Nurx reviews, not any one product

Sertraline HCl† is a medication that may be prescribed to treat depression and social anxiety disorder.

Depression Icon Depression
Social Anxiety Disorder Icon Social Anxiety Disorder
Pill Icon Pill

$25/month

As low as $0/month with insurance

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Medication shipped and billed every 1 or 3 months.
This treatment requires an online consultation with a Nurx medical provider. Cost may vary based on your insurance coverage, price not guaranteed. Not all insurance plans are accepted. Medication costs vary based on prescribed treatment and applicable insurance coverage and are shipped and billed separately as a 1-month or 3-month supply. Additional costs apply, including a monthly medication management fee.

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How sertraline HCl treats depression and anxiety*

  • Restores balance of serotonin to help with mood balancing
  • Can help you feel fewer symptoms of anxiety
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Did you know?

21 million US adults

have experienced at least one major depressive episode

5-12% of US adults

experience social anxiety at one point in their lives

Real patient stories

The science behind it‡

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Fact 01

Boosts serotonin levels

Sertraline HCl increases of levels of a neurotransmitter called serotonin in the brain.

Fact 02

SSRI antidepressant

This medication is part of a class of drugs called selective serotonin reuptake inhibitor.

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How to use sertraline HCl

It can take up to 2 weeks for your body to adjust to and experience the full benefits of this medicine.

Drug facts

STEP 1

Take as prescribed by your provider.

STEP 2

May be taken with or without food.

STEP 3

Depending on how you respond to treatment, your provider may start you on a lower dose and gradually increase your dosage.

How Nurx works◊

Find my treatment
1

Request treatment

Complete our online consultation, which
asks questions about your health history,
weight goals, and medication preferences.

2

Connect with a provider

After evaluating your consultation, a
provider licensed in your state will prescribe
a weight management treatment plan
(if clinically appropriate).

3

Get it delivered

We’ll send your prescription straight to your doorstep and check in with you to see how it’s working. You can reach out to your medical provider and adjust, pause, or cancel your treatment plan anytime.

4

Receive ongoing care

You’ll get support with progress tracking, educational content around healthy diet
and exercise, and appropriate treatment adjustments. We’ll also provide tips and 
treatment options for side effect management.

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100%

online care

2+ million

Nurx patients served

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Why Nurx?

Affordable

Quality treatment at an attainable price

Convenient

Easy refills & shipping to your door

Personalized

Providers help you find the right treatment

Supportive

Unlimited messaging for any questions, anytime

Common questions‡

See all FAQs
  • What is sertraline HCl?

    Sertraline HCl is an antidepressant used to treat depression, panic disorder, social anxiety disorder, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), and obsessive compulsive disorder (OCD). It may also be used in combination with other medications to treat premature ejaculation. This medication comes in tablet form, capsule, and oral solution.

  • How does sertraline HCl work?

    Sertraline HCl belongs to a class of medications called selective serotonin reuptake inhibitors (SSRIs). SSRIs increase levels of serotonin, a neurotransmitter that helps regulate mood. They are used to treat depression, panic disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), social anxiety disorder, and many other conditions.

  • What are the side effects of sertraline HCl?

    Side effects of sertraline HCl may include an upset stomach or nausea, fatigue, dry mouth, heartburn, and dizziness and sometimes weight gain or decreased libido. You may also experience sleep problems (insomnia), strange dreams or nightmares. If you experience any of these symptoms, talk to your doctor about possible changes to your medication dose.

  • How do I take sertraline HCl?

    Sertraline HCl is taken orally as a tablet. The recommended dose of sertraline HCl for anxiety disorders in adults is 50-200 mg/day. A lower dose of 25-50mg/day may be sufficient for many patients, but your provider will decide on an individual basis. Take as prescribed by your provider.

  • Can I take sertraline HCl with other medications?

    As with all medications, it’s vital to check that there are no potential drug interactions between your prescription and any supplements or other prescriptions you're taking. Always talk to your doctor before starting, stopping, or changing dosing on any medication. Similarly, never take another person’s medication or change your dosage without first consulting a physician.

  • Are there any risks when taking sertraline HCl?

    Pregnant and breastfeeding women should not take sertraline HCl because it can potentially cause serious side effects to an unborn child or newborn. If you're taking sertraline HCl and you plan on getting pregnant, contact your provider immediately.

  • How quickly does sertraline HCl work?

    Sertraline HCl affects several chemicals in your brain and central nervous system. It can take up to 6-8 weeks of using this to experience full effects, and you may see changes in your mood and behavior before it kicks in.

See all FAQs

Please note: Nurx does not provide therapy or counseling. Nurx is not available for crisis response. If you are experiencing a mental health crisis, please contact 911 or go to your nearest emergency department. IF YOU ARE CONTEMPLATING SUICIDE, CONTACT 911 OR CALL/TEXT THE NATIONAL SUICIDE PREVENTION LINE AT 988. These services are available 24/7.

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DR. GABRIELLA FARKAS, MEDICAL DIRECTOR

Meet your medical team

Gabriella Farkas, MD PhD is the Medical Director for Nurx’s mental health services. Dr. Farkas is a board-certified psychiatrist who advises the Nurx medical team on how to provide the highest quality of care for mental health conditions through telehealth.

†Sertraline HCl tablets (25mg, 50mg, 100mg), Rx only, treats depression, panic disorder, social anxiety disorder, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), and obsessive compulsive disorder (OCD. This drug may cause side effects, including but not limited to diarrhea, nausea, dry mouth, dizziness, drowsiness, fatigue, sleep problems, sexual problems. If you would like to learn more, see full prescribing information, here. You are encouraged to report negative side effects to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. If you’re experiencing a mental health crisis, please call 911 or go to your nearest emergency department.
*Individual results may vary.
‡The information provided here is not a substitute for professional medical advice, diagnosis, or treatment. You should not rely upon the content provided here for specific medical advice. If you have any questions or concerns, please talk to your provider.
◊Nurx does not provide talk therapy or crisis management. Services not offered in every state. Medications prescribed only if clinically appropriate, based on completion of the required consultation.

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At Nurx, we make it easy to get the expert healthcare you deserve. From schedules to health history, everybody is different—so we provide treatment and care that’s personalized to you. Through life’s cycles, changes, and transitions, we’re here to help you make informed choices about your health.

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