Rx
4.8 26,564 Nurx Reviews
Based on all Nurx reviews, not any one product
Rx

Compounded Semaglutide

4.8
26,564 Nurx Reviews
Based on all Nurx reviews, not any one product

A compounded GLP-1 injection for weight loss made with semaglutide,† the same active ingredient as Ozempic® and Wegovy®. Taken once weekly.

Weight loss
Injection

Starts at $199/month

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Compounded drugs are not FDA-approved or evaluated for safety, efficacy, or quality. Nurx compound drug offerings are not available to patients in California or Hawaii.

Medication cost may vary based on prescribed treatment, price not guaranteed. Medication shipped and billed monthly. Additional costs apply, including consultation, ongoing care, and side effect management.
Semaglutide starts at $199/month.

Compounded Semaglutide:
Know the basics

  • This medication mimics GLP-1, a 
naturally-occurring hormone in the body
  • Reduces appetite and food cravings to
help improve control of eating
  • May lower preference for fatty foods
  • Injection taken once per week
Find my treatment
Focus on quality and safety

Our base materials for compounded semaglutide are sourced only from FDA-registered manufacturers. Each batch is pharmacist reviewed and third-party tested to ensure quality and safety standards are met.

✔ Certificate of Analysis (CoA)

✔ Evaluated for sterility and potency

✔ Endotoxicity and pH tested

The science behind it

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FACT 01

Regulates appetite

Compounded semaglutide acts like the body’s GLP-1 hormone to help regulate appetite, calorie absorption, and storage.

FACT 02

Delivers full-body benefits

After meals, GLP-1 is released in the
small intestine and travels through the body to affect receptors in the brain, stomach, pancreas, heart, and more.

FACT 03

Takes cues from lizards

Seriously! The Gila monster (a lizard in
the southwestern US) inspired drugs like semaglutide as this animal can survive without food for long periods of time.

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What to expect with compounded semaglutide§

Compounded semaglutide only needs to be administered once per week. This medication can cause side effects, so it’s recommended to start with a low dose and gradually increase it over time to reach the target dose.

Your provider and care team will support each step of your treatment journey.

Drug facts

Your care team will check in regularly to see how you’re feeling and help you track your results.

When appropriate, your provider will facilitate updates to your dosage and treatment plan to ensure your progress.

If needed, your provider will help you address side effects with personalized guidance and treatment options.

Real patient stories

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Nurx patients served

How Nurx works◊

Find my treatment
1

Request treatment

Complete our online consultation, which
asks questions about your health history,
weight goals, and medication preferences.

2

Connect with a provider

After evaluating your consultation, a
provider licensed in your state will prescribe
a weight management treatment plan
(if clinically appropriate).

3

Get it delivered

We’ll send your prescription straight to your doorstep and check in with you to see how it’s working. You can reach out to your medical provider and adjust, pause, or cancel your treatment plan anytime.

4

Receive ongoing care

You’ll get support with progress tracking, educational content around healthy diet
and exercise, and appropriate treatment adjustments. We’ll also provide tips and 
treatment options for side effect management.

Find my treatment
Why Nurx?

Affordable

Safe, quality treatment at an attainable price with or without insurance

Convenient

Easy refills & free shipping to your door; pause or cancel anytime

Personalized

Providers with expertise in women’s health help you find the right treatment

Supportive

Unlimited messaging for questions, treatment adjustments, and side effect support

Common questions§

See all FAQs
  • What is a compounded GLP-1?

    A compounded GLP-1 is custom-made medication that mimics the action of the GLP-1 hormone produced by the body and can help to reduce appetite, decrease overeating, and lose weight. Compounded GLP-1s are allowed by law but are not reviewed by the FDA for safety and effectiveness. All of Nurx’s compounded medications are prepared by our partner pharmacy. 

  • How long do I need to take compounded semaglutide before I see weight loss?

    It’s possible to see weight loss in the first month of treatment. However, because everyone responds differently to medications, it may take some time to find the dose that works best for you. Most people lose weight with continued treatment after a few months. We recommend aiming for 1-2 pound weight loss per week, but your healthcare provider can provide personalized guidance based on your individual response.

  • What else does GLP-1 do? 

    • Helps control blood sugar by enhancing insulin secretion
    • Protects the heart, improves heart function, reduces blood pressure, and lowers risk for heart disease
    • Improves brain health, possibly by reducing inflammation and protecting nerve cells
    • Supports liver health including metabolic-associated fatty liver disease 
    • Reduces inflammation 
    • Helps with cholesterol (especially bad cholesterol)

  • What is a hormone?

    A hormone is a chemical messenger that travels through the blood to reach different organs and tissues. 

  • Do compounded GLP-1s have any known side effects?

    The good news is that most side effects are temporary and improve over time as your body gets used to the medication. The most common side effects include: 

    • Nausea
    • Diarrhea
    • Vomiting
    • Constipation
    • Stomach pain
    • Indigestion
    • Headache
    • Feeling dizzy, tired, or weak
    • Bloating
    • Burping
    • Gas
    • Heartburn
    • Runny nose or throat irritation

    Serious side effects are rare but can and do occur. Be sure to contact your provider or seek medical health if you experience:
    • Severe stomach pain (stabbing or knifelike)
    • Lump or swelling in neck, trouble swallowing, or short of breath
    • Yellow eyes/skin
    • Clay colored stools
    • Severe diarrhea
    • Continuous vomiting
    • Vomiting with blood
    • Fainting
    • Chest pain
    • Difficulty Breathing

    We are here to help you manage side effects. If you experience side effects, be sure to let your provider know as they can provide personalized guidance and educational content. They may even be able to prescribe treatment to help you manage these concerns.
    For any serious or severe side effects, please seek in-person medical care.

  • What happens if I experience side effects?

    To help mitigate any side effects you might experience from these medications, your provider will likely have you start with a low dose of treatment and gradually increase it over time to reach the target dose. If you do experience side effects, your provider can offer personalized guidance and resources to help. They also may prescribe treatment to help manage certain side effects if appropriate.

  • Can I use this medication if I’m pregnant or breastfeeding? 

    NO - Compounded semaglutide can harm a baby if taken during pregnancy. Stop taking compounded semaglutide as soon as you know you are pregnant. If you plan to get pregnant, stop taking compounded semaglutide at least 2 months before you start trying to conceive. This is important because it takes time for compounded semaglutide to leave your body. There is no data on the effects of compounded semaglutide in breast milk, so consider using other feeding methods while using these medications.

  • How will my GLP-1 medications be delivered?

    As GLP-1 injectables need to be refrigerated, your medication will be mailed through overnight shipping, and will be sent in temperature-controlled packaging. Once our partner pharmacy processes your prescription, you will receive your tracking ID from Nurx and will also receive real-time shipping notifications from the mail carrier to track timing of delivery. Please be sure you are home at time of delivery. Note, medication cannot be delivered to CA or HI and also cannot be delivered to PO box addresses.

  • How does Nurx ensure the quality of compounded GLP-1 medications?

    The quality of our compounded GLP-1 medications is of the utmost importance. Our base materials for compounded GLP-1s are sourced only from FDA-registered manufacturers. Each batch is pharmacist reviewed and third-party tested to ensure quality and safety standards are met. All batches receive a Certificate of Analysis (CoA), a document which confirms and summarizes all of the tests performed on a drug to confirm it meets required quality standards. All medication batches are tested for sterility, potency, pH, endotoxicity, and more.

  • What is a Certificate of Analysis (CoA)?

    A Certificate of Analysis (CoA) is a document which confirms and summarizes all of the tests performed on a drug to confirm it meets required quality standards.

  • How much does the program cost?

    The medical consult fee is a one time charge of $39. Patients will also be charged an ongoing care fee of $59/month. If you are prescribed compounded semaglutide, pricing starts at $199/month for lowest dose. Higher doses are $299/month.

See all FAQs
Hayley Miller, MD

Meet your medical team

“Each individual will have a unique experience with weight loss treatment. Our team is here to support each step of your journey to make sure you have everything you need to succeed.”

Dr. Miller is the Medical Director of Nurx Weight Management, advising Nurx’s medical team to provide the highest quality of care to help patients achieve their weight loss goals.

Talk to our experts

Not sure if this medication is right for you?

Connect with a Nurx provider for a personalized recommendation.◊
Explore treatment options

†Individual results may vary. Important drug safety and benefits information on semaglutide (1mg/ml and 2.4mg/ml injection for subcutaneous use, an Rx only compound drug, can be found here here. Semaglutide has not been FDA-approved or evaluated for safety, efficacy, or quality but can be used for weight loss. It may cause side effects including nausea, diarrhea, vomiting, and constipation. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
§The information provided here is not a substitute for professional medical advice, diagnosis, or treatment. You should not rely upon the content provided here for specific medical advice. If you have any questions or concerns, please talk to your provider.
◊Services and treatments not offered in every state, include medical treatment of overweight and obesity including lifestyle counseling (e.g., diet and exercise) and prescription medications, if clinically appropriate, based on completion of  required consultation. Nurx requires regular check-ins to monitor your progress.  Weight loss may be associated with other symptoms including but not limited to muscle loss, fatigue, menstrual changes, gallstones, and mood changes. Extreme/rapid weight loss may result in nutritional deficiencies that lead to hair loss, anemia, weak bones or increased risk of infection. Talk to your provider immediately about symptoms. Many people with overweight or obesity who lose weight have a tendency to regain all or some of the weight over time. Overweight and obesity medication efficacy increases with the addition of diet and exercise. Individual response to treatment may vary and is not guaranteed by Nurx.
Compounded drugs are not FDA-approved or evaluated for safety, efficacy, or quality. Nurx compound drug offerings are not available to patients in California or Hawaii.

Exceptional care at every step

At Nurx, we make it easy to get the expert healthcare you deserve. From schedules to health history, everybody is different—so we provide treatment and care that’s personalized to you. Through life’s cycles, changes, and transitions, we’re here to help you make informed choices about your health.

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